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Postdoctoral Research Fellow- Department of Biochemistry and Molecular Biology- Lab of Dr. Fadia Ibrahim

Responsibilities

Job Summary:

A Postdoctoral position is immediately available in the laboratory of Dr. Fadia Ibrahim in the Department of Biochemistry & Molecular Biology at Thomas Jefferson University. Our research program focuses on elucidating the molecular mechanism of a novel RNA decay process named "Ribothrypsis" (Nature Struc. Mol. Biol. 2018), and the role of RNA dysregulation in neurodegeneration. We employ multi-approaches of molecular, biochemical, and novel RNA sequencing methods (Nature Protoc. 2019, Nucleic Acids Res. 2021), and utilize multiple model systems. This exciting opportunity offers a unique chance to contribute to cutting-edge research at the intersection of RNA decay and neurodegenerative diseases.

Key Responsibilities:

• Conduct independent research to unravel the molecular mechanism of Ribothrypsis.
• Employ state-of-the-art techniques in molecular biology, biochemistry, cell culture, and novel next-generation sequencing (NGS) techniques.
• Collaborate with a multidisciplinary team and participate in data analysis/interpretation, presentation in professional meetings, and publication of research findings.

Qualifications

• PhD. in molecular biology, biochemistry, neuroscience, or related fields.
• Strong skills in molecular biology, biochemistry, and tissue culture techniques.
• Experience in NGS library generation (e.g., RNA-Seq, Ribo-Seq, HITS-CLIP), and knowledge of NGS technologies (e.g., Illumina, Oxford Nanopore Technology) is preferred.
• Experience in data processing and analysis of NGS reads is a plus.
• Strong organization and communication skills and ability to work in a team.
• Publication track-record in relevant fields.

Interested applicants please submit a CV, cover letter describing your research interests and career goals, and contact information of three references in a single PDF file.

Closing Statement

Jefferson includes Thomas Jefferson University and Jefferson Health, a dynamic university and health system with broad reach across the Delaware Valley. Jefferson is the second largest employer in Philadelphia and the largest health system in Philadelphia based on total licensed beds.

Through the merger of Thomas Jefferson University and Philadelphia University in 2017, our University includes ten colleges and four schools. We are an NCAA Division II university and an R2 national doctoral university offering undergraduate and graduate-level programs that provide students with a forward-thinking education in architecture, business, design, engineering, fashion and textiles, health, medicine and social science.

Jefferson Health, the clinical arm of Thomas Jefferson University, has grown from a three-hospital academic health center in 2015, to an 18-hospital health system through mergers and combinations that include hospitals at Abington Health, Aria Health, Kennedy Health, Magee Rehabilitation and Einstein Healthcare Network. We have over 50 outpatient and urgent care centers; ten Magnet®-designated hospitals (recognized by the ANCC for nursing excellence); the NCI-designated Sidney Kimmel Cancer Center (one of only 70 in the country and one of only two in the region); and one of the largest faculty-based telehealth networks in the country. In 2021, Jefferson Health became the sole owner of HealthPartners Plan, a not-for-profit health maintenance organization in Southeastern Pennsylvania. We are the first health system regionally to create an aligned payer-provider partnership.

Jefferson's mission, vision and values create an organization that attracts the best and the brightest students, faculty, staff, and healthcare professionals, as well as the most visionary leaders to drive exceptional results.

• OUR MISSION: We improve lives.
• OUR VISION: Reimagining health, education and discovery to create unparalleled value
• OUR VALUES: Put People First, Be Bold & Think Differently and Do the Right Thing

As an employer, Jefferson maintains a commitment to provide equal access to employment. Jefferson values diversity and encourages applications from women, members of minority groups, LGBTQ individuals, disabled individuals, and veterans.